Vortex deployed at the Institute for Molecular Bioscience, University of Queensland

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Dotmatics, a provider of scientific informatics solutions and services, recently announced that the Medicinal Chemistry and Drug Development research group at the Institute for Molecular Bioscience, University of Queensland, has deployed Vortex, Dotmatics’ scientific intelligence and analytics solution.

Infectious disease remains the second leading cause of death globally. The increase in multidrug-resistant (MDR) bacteria and the decline in effective therapies have resulted in ‘the superbug crisis.’ Research conducted by Prof. Cooper’s team has led to the discovery of several drug candidates against anti-infective diseases.

The team is also spearheading a global initiative, Worldwide Antibiotic Discovery Initiative for the discovery and development of new therapies against multidrug-resistant (MDR) microorganisms. This complex research encompasses the analysis of large amounts of biological and chemical data. Dotmatics’ Vortex provides Prof. Cooper’s team with an essential tool to perform complex data mining, analysis and visualisation, enabling the scientists to find unique trends and identify lead compounds in an effective way.

“We have large data sets generated from our high-throughput antimicrobial screening facility and multiple collaborative development projects, as well as the integration of publicly available data. Statistical analysis and visualisation of the data thereby plays a crucial role in the decision making process of selecting and progressing drug candidates,” said Prof. Cooper. “The Dotmatics Platform has an important role in the team as it assists the decision making process by providing a comprehensive and interactive visualisation tool to our medicinal chemists.”

“We are very pleased to continue our expansion in Australia and proud to have been selected by Prof. Cooper’s team to provide solutions to assist with his complex research of anti-infective drug candidates,” said Dr Mike Hartshorn, CSO at Dotmatics. “We invest strongly in developing great informatics solutions for the scientific community and are thrilled to learn that world class researchers across all continents are using Vortex and the Dotmatics Platform to accelerate their studies.”

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