Thermo Electron has launched Galileo LIMS v 3.1, providing additional functionality to increase efficiency in the demanding high-throughput environment of in vitro ADME/Tox discovery laboratories.
Highlights of the latest release of this LIMS product include: automatic results flagging, using a three-colour system to indicate acceptance, rejection or flagging of results; rapid study entry to accelerate the entry of concentration or raw data from analytical instrument into the LIMS; the addition of IC50 shift – a new experiment type to elucidate enzyme inactivation; and support for PAMPA permeability studies that are important in early screening of compounds.
In addition, Galileo now interfaces with more analytical instruments, including a bi-directional digital interface to Xcalibur v 1.4 and 2.0, the controlling software for Thermo’s line of mass spectrometers.
Introduced in mid-2003, Galileo allows users to plan, design, calculate, graph and report in vitro ADME/Tox data in a single application. The experimental procedure and definition of samples, creation of analytical run worklists, interfacing to analytical instruments such as LC-MS and plate readers, creation of calibration curves, and calculation of final results can be performed by Galileo and saved to the Oracle database.