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Rats tracked with aid of visualisation tools

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The Rat Genome Database at the Medical College of Wisconsin has published a rat signalling pathway diagram collection created with Ariadne Pathway Studio. The pathways are available on the Rat Genome Database website. Each diagram is interactive, linked to detailed information about proteins, relationships, and related pathways.

Victoria Petri from the Rat Genome Database said: 'Besides the largest collection of molecular interactions referenced by original literature sources, it includes powerful visualisation tools and can produce interactive HTML pathways with underlying reference information in just one click.'

The rat signalling pathways were curated from the literature by RGD staff. Interactive diagrams linked to gene reports at RGD were created using Ariadne’s ResNet Mammalian database, which has more than a million unique interactions between proteins, small molecules and cell processes, and the Pathway Studio visualisation tools.

Currently the Rat Genome Database has published 13 interactive signalling pathway diagrams. Additional pathways will be added on a regular basis.