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Nexus Copy Number 5.1

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Version 5.1 of the Nexus Copy Number software, an application for DNA copy number analysis, has been released by BioDiscovery. This latest version has improvements to the previous user interface, allowing for detailed information about a sample and calls to be available at the user's fingertips so that they can efficiently review samples, identify possible pathogenic regions, compare with already processed samples, obtain annotations from many external databases and easily generate customised reports.

Improvements to processing include the new FASST2 segmentation algorithm, incorporation of PennCNV processing, and support for Affymetrix OncoScan (MIP technology) arrays. With new pre-processing steps, the software can adjust for samples with aneuploidy and correct for any systematic biases, such as GC wave patterns, and samples with a lot of artifacts can be salvaged to extract high-quality data for reliable results.

Nexus Copy Number can integrate and process together, in a single project, data from commercial array platforms such as Agilent, Affymetrix, Illumina, Roche NimbleGen, Next Gen read depth, as well as custom arrays. It has free access to a web-based repository for querying and storing genomic data from any location and is applicable to a range of study types from focused projects of a cytogeneticist to large-scale cancer or GWAS research.

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