Thermo Electron has launched its QuickQuan software for automating high-throughput LC-MS/MS assays in early drug discovery. The combination of QuickQuan's rapid compound tune and optimisation time with Thermo's Finnigan TSQ Quantum triple quadrupole mass spectrometer is key to automatically assessing new chemical entities (NCEs) in early drug-development assays such as metabolic stability.
QuickQuan delivers rapid LC-MS/MS optimisation through use of an automated on-line infusion mode and valve switching design. This allows for precise auto-tuning with high sensitivity that, consequently, maximises successful automated quantification of chemically diverse compounds. All analytical information is stored either in Microsoft Access or Oracle databases, which facilitates rapid data exchange across global networks.