CLC bio and BioBam Bioinformatics have introduced an integrated workflow for researchers working with non-model organisms without reference sequences. By combining the Blast2GO PRO plugin and CLC Genomics Workbench, this workflow allows users to combine and integrate NGS bioinformatics data analyses on one platform, covering the entire data analysis workflow from NGS data quality control and assembly to genome-wide functional annotations and interpretations of genomes and transcriptomes.
‘Our department focuses on species that are relevant in an ecological and evolutionary context, but they are not always classical model organisms of molecular biology. For us, CLC Genomics Workbench and Blast2GO PRO are crucial tools for the analysis of de novo transcriptome data,’ said Dr Ewald Große-Wilde from the Department of Evolutionary Neuroethology at the Max Planck Institute for Chemical Ecology. ‘The new CLC Blast2GO PRO plugin allows easier integration of these two tools, reducing the ab initio time from sequence acquisition to annotation results. Furthermore, this plugin has become indispensable in ongoing gene expression profiling studies of non-model species, because it enables us to identify potentially relevant target genes with ease.’
Throughout October 2013, customers can procure the Blast2GO PRO plugin for free for one year, if they purchase a license for CLC Genomics Workbench.