CLC bio has released its Next Generation Sequencing (NGS) solution, CLC Genomics Workbench, which incorporates cutting-edge technology and algorithms, while also supporting and integrating with the rest of a typical NGS workflow.
CLC Genomics Workbench is the first comprehensive analysis package, which can analyse and visualise data from all the major NGS platforms, such as SOLiD by Applied Biosystems, 454 GS flx by Roche Applied Science, Solexa by Illumina, and HeliScope by Helicos.
In benchmark tests, CLC bio has assembled half a million 454 reads against the full E.coli reference genome in around two minutes on a dual-core computer with one gigabyte RAM. This speed-up, based on integrated SIMD high-performance computing technology, increases even more when using a computer with more CPU-cores and RAM. CLC bio expects to release a benchmark white paper in the near future.
CLC Genomics Workbench 1.0 takes full advantage of ‘paired end’ data, and supports a number of features and work-tasks, such as reference assembly of genomes, de novo assembly of genomes, SNP detection using advanced models, multiplexing, and high-throughput trimming.