The world’s first collaborative effort that combines non-mathematical heuristic modelling with mathematical modelling to increase the success rates of drug discovery and formulation development by pharmaceutical and cosmetic industries has been announced. Bio-Modeling Systems, a leading integrative systems biology company and Persistent Systems, a global leader in software product and technology services, have launched the joint systems biology research and development initiative.
Bio-Modeling Systems’ team of biologists will combine the outputs of its CADI (computer assisted deductive integration) proprietary heuristic modelling platform with a powerful new software platform, Cell-in-Silico, developed by Persistent. This will result in the first heuristic model of skin cell interplay mechanisms to be enhanced through mathematical modelling. This strategic collaboration harnesses the scientific and bioinformatics capabilities of Bio-Modeling Systems and the information technology and scientific capabilities of Persistent Systems to provide what the companies state are the first truly holistic systems-based drug discovery solutions.
‘Bio-Modeling Systems and Persistent Systems have come together to develop a much needed solution that will address the pharma and cosmetic industries’ need for predictive modelling of skin in silico,’ said Dr Anand Deshpande, managing director and CEO, Persistent Systems. ‘Bio-Modeling Systems’ scientists have pioneered heuristic biological modelling with their CADI platform. By coupling this with Persistent Systems’ strength in mathematical modelling and IT, we will develop a viable in silico alternative to animal testing.’