Applied Biosystems’ Software Development Community has made formal agreements with Geospiza and GenomeQuest to develop bioinformatics tools for analysis and management of data generated by the SOLiD System, a high throughput next-generation sequencing system. The new relationships should help scientists to realise the full potential of next-generation genomic analysis.
Through its Software Development Community, Applied Biosystems is one of the first manufacturers of next-generation instrument systems to make software development tools and resources widely available to the bioinformatics community. Established in 2006, this community supports life scientists and independent software vendors to develop and commercialise innovative bioinformatics applications for next-generation genomic analysis platforms.
As part of its participation in the Software Development Community, Geospiza has developed a software system to automate sequencing workflows for capillary electrophoresis (CE) instrumentation, and will expand its relationship with Applied Biosystems to include next-generation sequencing instruments. Processing both CE and SOLiD data through a single data processing pipeline will enable researchers to integrate and visualise data sets from both technologies.
GenomeQuest has an integrated sequence information solution which, based on its database of reference sequences, can transform raw sequence data from the SOLiD System into insightful information. GenomeQuest’s platform should also help SOLiD System users with sequence alignment and analysis, offering increased productivity, and enabling scalability as customers increasingly use next-generation genomic analysis platforms.
The SOLiD System, based on sequencing by oligonucleotide ligation and detection, is Applied Biosystems’ next-generation system for ultra high throughput genomic analysis. The SOLiD System uses a technology called stepwise ligation, which generates high quality data for applications, including whole genome sequencing, chromatin immunoprecipitation (ChIP), microbial and eukaryotic resequencing, digital karyotyping, medical sequencing, genotyping, gene expression and small RNA discovery.