Issues

Browse our previous issues below, or browse and search for specific features or analysis & opinion.

All our articles, news, product announcements and more are available from the navigation at the top of the site (accessible via the menu button for smartphone or tablet).

Access is free when subscribed and logged in.

PRACE encourages industry

Robert Roe speaks with Lee Margetts, chair of PRACE’s industrial advisory committee, about its work to increase the engagement of industrial HPC users

Mapping infection

Clare Sansom discusses the use of computational tools to help researchers map and treat infectious diseases

Controlling your data

Sophia Ktori takes a look at technology which helps labs carefully manage and store data securely

Supporting science

Robert Roe looks at HPC technologies that could enable the next generation of scientific breakthroughs

Oil Change

As the world makes better use of renewable energy, the Oil and Gas market aims to use more simulation to ensure sound decision making, writes Gemma Church

Specifying and Building the smart laboratory

This chapter looks at how to build a smart laboratory; what approaches to take; and how to deal with potential problems. Becoming ‘smart’ takes time, not only due to the level of investment required, but also because of the impact of change and the need to consider legacy requirements.

 

Beyond the laboratory

This chapter considers who cares about how smart the laboratory is, and why? It also looks at the broader business requirements and their impact on the laboratory, with an emphasis on productivity and business efficiency, integration with manufacturing and business systems, patent evidence creation, regulatory compliance, and data integrity and authenticity

Laboratory informatics tools

This chapter will look at the four major laboratory informatics tools – laboratory information management systems (LIMS), electronic laboratory notebooks (ELNs), laboratory execution systems (LES) and scientific data management systems (SDMS) – their differences and how they relate to each other. Each of these systems functions at or around the ‘Information’ layer (see Figure 1) and typically serves to collate data and information about the laboratory’s operations

Document management

This chapter considers how the smart laboratory contributes to the requirements of a knowledge eco-system, and the practical consequences of joined-up science. Knowledge management describes the processes that bring people and information together to address the acquisition, processing, storage, use, and re-use of knowledge to develop understanding and to create value

Instrumentation

This chapter will consider the different classes of instruments and computerised instrument systems to be found in laboratories and the role they play in computerised experiments and sample processing – and the steady progress towards all-electronic laboratories. 

However, the choice of best-of-breed laboratory instruments and instrument systems can present challenges when it comes to getting everything to work together in a seamless way. The final part of this chapter will look at the issue of standard data interchange formats, the extent of the challenge, and some of the initiatives to address them

 

The smart laboratory

This chapter discusses what we mean by a ‘smart laboratory’ and its role in an integrated business. We also look at the development of computerised laboratory data and information management; the relationships between laboratory instruments and automation (data acquisition); laboratory informatics systems (information management); and higher-level enterprise systems and how they align with knowledge management initiatives.

Dealing with data

Informatics experts share their experiences on the implementation of new technologies and managing change in the modern laboratory

An introduction to building a smart laboratory 2019

This chapter serves as an introduction to this guide, Building a Smart Laboratory 2019. We hope to highlight the importance of adopting smart laboratory technology but also to guide users through some of the challenges and pitfalls when designing and implementing paperless technologies in the laboratory.

Data analytics

This chapter takes the theme of knowledge management beyond document handling into the analysis and mining of data. Technology by itself is not enough – laboratory staff need to understand the output from the data analysis tools – and so data analytics must be considered holistically, starting with the design of the experiment

Summary

In this guide we have attempted to coalesce much of the information required in order to design and implement as smart laboratory or, at the very least, to begin the process of laboratory automation. While it may seem like a challenging prospect, the underlying principles are simple and focused on crafting a strategy that will enable more productivity and insight to be generated from scientific research

The Need for Speed

Simulation and modelling increasingly expedite widespread change across the automotive industry, writes Gemma Church

Laboratory in the cloud

Cloud-based informatics software is growing fast thanks to highly flexible and customisable deployment methods, writes Sophia Ktori

Storage in life sciences

With data rates increasing and more complex challenges arising in life sciences, Robert Roe speaks with Panasas’ Jim Donovan and Dale Brantly about the benefits of using HPC for these workloads

Managing HPC resources

As HPC systems get larger and more complex, companies are developing services and tools to help users manage their resources effectively, writes Robert Roe

Reprogrammable HPC

FPGAs provide an early Insight into possibile architectural specialisation options for HPC and machine learning, writes Robert Roe

Expect Exascale

Robert Roe looks at advances in exascale computing and the impact of AI on HPC development

The imperfect storm

Gemma Church investigates modelling and simulation tools required for accurate weather prediction

Learn to fly

Gemma Church looks at modelling and simulation software in the aerospace industry

Life and LIMS

Sophia Ktori speaks to laboratory informatics experts about the development of Laboratory Information Management SYSTEM

Research misconduct

Mark Newton, a consultant from Heartland QA, gives his take on the scale of research misconduct taking place in laboratories

Managing pharma data integrity

Darren Barrington-Light, senior manager product marketing for Thermo Fisher Scientific, explains the importance of integrating a LIMS software package into the pharmaceutical data chain 

A look to the future

Robert Roe speaks with laboratory informatics software providers about the future of their software and the introduction of new technologies, such as AI and deep learning

Model Medical Devices

Gemma Church reveals how simulation and modelling are aiding the design and development of a range of medical devices

Applying AI

Sophia Ktori completes her two-part series on the use of artificial intelligence in healthcare research

Looking ahead

Robert Roe looks at technology that could disrupt the HPC ecosystem

A flash in the pan

As storage technology adapts to changing HPC workloads, Robert Roe looks at the technologies that could help to enhance performance and accessibility of storage in HPC

Simulating the future of cycling

By using simulation software, road bike manufacturers can deliver higher performance products in less time and at a lower cost than previously achievable, as Keely Portway discovers

ISC Show report

Robert Roe reports on developments in AI that are helping to shape the future of high performance computing technology at the International Supercomputing Conference

A standard approach

Sophia Ktori concludes her two-part series exploring the use of laboratory informatics software in regulated industries.

Roofline Estimation

James Reinders is a parallel programming and HPC expert with more than 27 years’ experience working for Intel until his retirement in 2017. In this article Reinders gives his take on the use of roofline estimation as a tool for code optimisation in HPC

Pages