The heart is a prime example of art/science crossover. During the month of February, readers are likely to be surrounded by stylised images of the human heart. For societies derived from West European cultural traditions, the heart is currently (it has not always been so) the symbolic seat of affection. The heart also symbolises courage (Lionheart, Braveheart, and so on). The Tin Woodsman in The Wizard of Oz1 is seeking a heart in both those senses.
January/ February 2005
Some article topics lead inexorably to the thesaurus, dictionary of quotations, and store of bad puns. Heart of the matter? Heart for heart's sake? The beat goes on? Whatever ... the nearness of this issue to Valentine's Day provides an ideal opportunity to explore in more detail the field of cardiac simulation featured in the Summer 2004 issue of our Life Science IT supplement. Clare Sansom's article 'The Virtual Human' reported the pioneering career of Professor Denis Noble.
LIMS has really grown up. When I started (more than 20 years ago, a depressingly long time...), LIMS was virtually unknown. In fact, it took me months to drum up the courage to ask what the letters LIMS stood for. 'L' is obviously 'Laboratory', and 'I' is probably Information, 'M' might be 'Management', but what was 'S'? Anyone that even mentioned LIMS talked about 'LIMS Systems', so the 'S' couldn't be 'System'. Perhaps 'Software'?
The US Food and Drug Administration has been prone throughout its history to strong policy swings that can catch drug companies off guard. A move towards more industry-friendly, good manufacturing guidelines has been well signposted over the past two years. Even though it sounds like good news, the new approach is still confusing companies trying to comply with existing regulations governing electronic records. This year should see a clearer picture emerging, but companies may have to abandon old habits and curtail the use of some popular software if they are to keep up with the changes.