IMAGE ANALYSIS AND PROCESSING

Tissue Studio 2.0

16 August 2010

Definiens

Definiens has introduced its Tissue Studio 2.0, the latest version of the company's image analysis software for digital pathology.

First introduced in 2009, Tissue Studio is a comprehensive image analysis software for biomarker translational research. In a wide array of different tissue stains, the out-of-the-box software automatically and accurately detects and measures cells and sub-cellular components within regions of interest; it provides cell-by-cell quantification of protein expression and describes cellular morphology.

Along with improved processing speed, version 2.0 of the software now includes a full range of functionality for the analysis of immunofluorescence tissue stains. Up to 12 immunofluorescence channels per image are supported. It also includes more accurate nucleus detection. maintains the system's easy-to-use interface and streamlined workflow. With its 'learn-by-example' format, users train the software to identify representative regions of interest, and configure it to automatically identify cells and sub-cellular objects. Beside the analysis of whole virtual slides, Tissue Studio 2.0 also provides full support to process tissue micro arrays. Pathologists do not need prior computer programming, and can develop customised image analysis solutions in as little as 20 minutes.

The company states that beta testers of the latest version of Tissue Studio 2.0 at the University of Edinburgh utilised the software in the cell-by-cell analyses of immunohistochemistry (IHC) and immunofluorescence assays derived from cell cultures and tissue specimens. The software successfully measured morphological changes to provide researchers with a detailed understanding of the dynamics of cellular change.

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