BIOINFORMATICS

GenomeQuest ChiP-Seq

14 December 2009

GenomeQuest

GenomeQuest has introduced a ChiP-Seq workflow solution available as a web cloud service, providing tools for alignment, peak modelling and interactive analysis. To maximise accuracy, it allows for more than 15 key parameters to be set and multiple runs to be stacked and analysed collectively. Also, researchers can immediately share and connect their results with other sequence databases, GenomeQuest workflows, and colleagues – preserving and leveraging their work.

This full workflow is delivered in an easy-to-use, integrated environment. From a web browser, researchers simply upload their database and fill out two forms – one each for alignment and peak modelling. For the reference databases, users can select from a list of GenomeQuest aggregated and qualified databases with extended annotations. The environment also includes an interactive sequence browser where researchers query and analyse run results.

The interactive sequence browser of the ChIP-Seq workflow includes a table of peak modelling results with columns for gene name and description, chromosome, peak start and stop position, peak length and high point, and all peak statistics. After their analysis, researchers can save all or part of this table as a new annotated database and share it as a reference for follow-on work.

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