IMAGE ANALYSIS AND PROCESSING

Definiens Tissue Studio

16 September 2009

Definiens

Definiens has introduced Definiens Tissue Studio, a digital pathology image analysis software package for translational biomarker research.

Definiens Tissue Studio is an out-of-the-box software application for digital pathology image analysis that supports a wide array of tissue stains including blue, brown, and red, as well as H&E (hematoxylin and eosin stain) and IF (immunofluorescence). Utilising the new Definiens Composer Technology, Definiens Tissue Studio is able to identify highly heterogeneous tissues - and the individual cells and sub-cellular objects within them - to conduct extremely accurate cell-by-cell measurements. The software supports common tissue formats including slides and TMAs, and is compatible with all image formats from Aperio, Hamamatsu, Zeiss, Applied Imaging, Bacus, TissueGnostics, and generic file formats (.tiff, .jpeg).

Definiens Tissue Studio is optimised for cell-by-cell biomarker quantification and incorporates a new, simplified interface. Pathologists need no computer programming expertise to teach the application to identify regions of interest (ROI). The application enables users to work with up to four images simultaneously, allowing for rapid identification and quantification of biomarkers in cellular and sub-cellular compartments. The application can then be used in 'batch mode' for automated parallel processing either locally or on a server cluster. The process allows researchers to quickly create sophisticated, robust image analysis solutions that can uncover clinically relevant, quantitative biomarker attributes.

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