BIOINFORMATICS

Qlucore Omics Explorer

15 July 2009

Qlucore

Qlucore Omics Explorer 2.0, from Qlucore, is an enhanced data analysis tool developed for the life science and biotech industry, allowing researchers to shorten analysis time and add more creativity to research.

This latest version of Qlucore's software (previously known as Qlucore Gene Expression Explorer) will enable researchers to explore different hypothesis and alternative scenarios within seconds. The software will therefore be invaluable for unveiling important new discoveries, as it will allow the actual researchers – the people with the most biological insight – to study the data and to look for patterns and structures, without needing to be a statistics or computer expert.

The latest enhancements to Qlucore Omics Explorer mean that the software can provide researchers with very powerful (and highly interactive) hierarchal clustering capabilities. The results are presented both as cluster trees and as a heatmap. The heatmap view works in full synchronisation with each of the other four plot types (PCA sample, PCA variable, scatter and data table).

Researchers can work simultaneously with all five plot types – all of which can be fully synchronised – even if the most common usage will include a subset. As such, if a researcher uses the software's powerful statistical filters, or wishes to deselect a sample group, all five plots are immediately updated to reflect this new point in the analysis. Scatter plots, which can be used to plot how one variable is distributed over a group of samples, represent another new plot type in Qlucore Omics Explorer 2.0. With scatter plots, the grouping is freely selected among the annotations available for samples.

Scatter plots are good for quality control and for presenting key findings and results. Also new in Qlucore Omics Explorer 2.0 is a powerful log function that allows users to restore their research to an earlier point in their analysis. Since many users often work on parallel projects, it is important to keep track of the analysis steps. As a result, Qlucore Omics Explorer 2.0 gives the user full freedom to explore data in their own way, with the log function available to ensure that the user can document exactly which steps have been taken, without being forced to follow a single path.  

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